Ibuprofen on an Empty Stomach: Safety, Research, and More
Ibuprofen is among the most commonly used over-the-counter (OTC) medicines that combat inflammation, pain, and fever. It’s been used for over 50 years.
Ibuprofen is an nonsteroidal anti-inflammatory medication (NSAID), and is effective by inhibiting the cyclooxygenase (COX) the enzyme’s activity. COX activity is the reason for the production of prostaglandin.
If ibuprofen is safe enough to consume in the absence of food is dependent on the individual and specific factors that increase the risk.
Let’s have a look at the most effective way to take ibuprofen in order to reduce symptoms and reduce the risk.
Ibuprofen is been identified as a very low risk that it can cause severe gastro (GI) adverse effects in general. However, there are risks and are based on the person’s age, the length of time of usage, dosage as well as any existing health issues.
Ibuprofen can alter prostaglandin levels and trigger GI adverse reactions. Prostaglandin’s primary function is to protect the stomach. It helps reduce stomach acid, and also increases the production of mucus.
When ibuprofen is used in large amounts or for an extended period of period of time, less prostaglandin gets produced. This can cause stomach acid to rise and cause irritation to the stomach’s lining which can cause issues.
The effects of GI can be contingent on many factors, such as:
- The duration of duration of. If you take ibuprofen over longer periods of time, the risk of GI-related issues increaseTrusted Source in comparison to shorter-term use for needs that are immediate.
- Dosage. Taking higher doses for prolonged periods of time can increase the risk of developing GI-related issues.
- Other health issues. Being a victim of certain health issues like the ones listed below are a risk factor for adverse reactions or side effects:
- the history of GI complaints
- bleeding ulcers
- chronic chronic inflammatory bowel disease
- Personal elements. The older population is at a higher chance of GI as well as other side consequences of ibuprofen.
- Make sure you discuss the benefits of ibuprofen and any potential risks with your doctor before you start taking this medication.
- If you suffer from heart kidney disease, kidney problems or kidney disease, high blood pressure or other chronic medical issues consult your physician regarding the use of ibuprofen.
The two COX types are distinct kinds of COX and they have distinct effects within the body. COX-2, when activated inhibits the release of prostaglandin in the response to fever, pain and inflammation. COX-1 exerts a protective function over the stomach’s lining as well as the surrounding cells.
Ibuprofen alters COX-1 as well as COX-2 activities, providing relief from symptoms, while simultaneously increasing the risk of adverse reactions to certain medications.
When you are taking a medication from a trusted source, it can have an impact in absorption, efficacy and adverse consequences. This can be done by taking it when you eat or with a stomach empty.
One of the problems with ibuprofen is that if you consume it orally, it isn’t absorbed quickly. It takes about 30 minutes to get the effect. This is crucial when you require immediate relief from pain.
Ibuprofen may cause a number of GI adverse effects, such as:
- nausea and vomiting
- rupture in stomach or small intestine or the large intestine
- sensation of being full
Lower and upper GI risk factors must be considered prior to taking Ibuprofen. Ibuprofen does not have the benefit of a lower GI risk. It is not recommended by Trusted Source in the case of risk of lower GI, even when using proton pump inhibiting medication such as Nexium to provide protection.
RisquesTrusted source of the GI side effects is higher when you:
- seniors who are over 65, as they are at risk of bleeding in the GI Source increases by quadruple
- The history of heartburn or indigestion
- the use in the use of corticosteroids, anticoagulants such as warfarin (Coumadin), selective serotonin Reuptake Inhibitors (SSRIs) like sertraline (Zoloft) and antiplatelets such as aspirin or Clopidogrel (Plavix)
- Peptic ulcer or bleeding related to ulcers
- Alcohol consumption, because it may cause irritation to the stomach lining. Also, drinking alcohol with ibuprofen can increase the risk of stomach bleeding
Keep in mind that some medications interact with ibuprofen as well as health issues. Make sure you discuss the best choices to reduce your chance of GI issues with your physician first.
If you are experiencing mild symptoms of stomach discomfort Some medications for stomach protection may assist:
- The magnesium-based anti-inflammatory can ease the mild symptoms of heartburn or acid reflux. Avoid taking antacids containing aluminum along with ibuprofen as they can interfere with the absorption of ibuprofen.
- An proton pump inhibitor like esomeprazole (Nexium) may help in treating acid reflux. Make sure to consult your physician about any possible side reactions or drug interactions.
A word of caution: Don’t take multiple kinds of acid reducers at the at the same time. If your symptoms don’t get better or worsen consult your physician.
The most effective method to take Ibuprofen will depend the age of your patient and other risk factors. Studies from Trusted Source shows that taking ibuprofen in conjunction together with a stomach protector like PPI PPI is a great way to prevent peptic ulcers especially if you’re taking it at larger doses over a prolonged period of time.
If you’re taking Ibuprofen for temporary pain relief, and you have no risks, you might be capable of taking it with food for quicker improvement. SymptomTrusted source improvement. Magnesium-based protectants can aid in quicker relief.
It is important for you to see a doctor in case you
- Have black tarry stool
- are vomiting blood
- are suffering from extreme stomach pains
- are suffering from an incessant nausea and nausea and vomiting
- You may have blood in your urine.
- Have chest pains
- Have trouble breathing
Side effects from the stomach are among the most frequent complaint with Ibuprofen. It’s crucial to know that the severity or seriousness of GI issues, like bleeding, may occur without warning.
Make sure you talk about your digestive issues with your healthcare doctor prior to taking ibuprofen on your own. If you’re expecting, speak to your physician prior to taking Ibuprofen.
In some cases in order to speedily relieve discomfort, taking ibuprofen with an empty stomach could be a good idea. An magnesium-containing an antacid can offer protection and provide quicker relief.
If you are using the product for a long time it is recommended to take precautions to prevent GI adverse negative effects. In certain instances the doctor may recommend an alternative medication.